Arai Kenta
- 准教授
- 学位:博士(理学)
基本情報
所属
- Undergraduate School of Science / Department of Chemistry
- Graduate School of Science and Technology / Course of Science and Technology
- Graduate School of Science / Course of Chemistry
ジャンル
- Chemistry
研究と関連するSDGs
詳細情報
研究キーワード
- Protein folding
- Enzyme model
- Neurodegenerative diseases
- Peptide synthesis
- Flow chemistry
研究分野
- Life sciences Bioorganic chemistry
受賞
- TU Science Award 2020
- SeS redox & catalysis Bentham Current Green Chemistry Award for an excellent poster presentation
論文
Diselenide-bond replacement of the external disulfide bond of insulin increases its oligomerization leading to sustained activity
Resin-supported cyclic telluride as a heterogeneous promoter of disulfide formation under solid–liquid biphasic conditions
Semi-enzymatic acceleration of oxidative protein folding by N-methylated heteroaromatic thiols
Small Organoselenium Catalysts as a Potential Manipulator for Redox Homeostasis and Proteostasis
Modeling Type‐1 Iodothyronine Deiodinase with Peptide‐Based Aliphatic Diselenides: Potential Role of Highly Conserved His and Cys Residues as a General Acid Catalyst
Redox Chemistry of Selenols and Diselenides as Potential Manipulators for Structural Maturation of Peptides and Proteins
S ‐Denitrosylase‐Like Activity of Cyclic Diselenides Conjugated with Xaa‐His Dipeptide: Role of Proline Spacer as a Key Activity Booster
Abnormal Enhancement of Protein Disulfide Isomerase-like Activity of a Cyclic Diselenide Conjugated with a Basic Amino Acid by Inserting a Glycine Spacer
Flexible Folding: Disulfide-Containing Peptides and Proteins Choose the Pathway Depending on the Environments
Glutathione peroxidase-like functions of 1,2-diselenane-4,5-diol and its amphiphilic derivatives: Switchable catalytic cycles depending on peroxide substrates
Relaxin-2 May Suppress Endometriosis by Reducing Fibrosis, Scar Formation, and Inflammation
Basic Amino Acid Conjugates of 1,2-Diselenan-4-amine with Protein Disulfide Isomerase-like Functions as a Manipulator of Protein Quality Control
Cover Feature: Modeling Thioredoxin Reductase‐Like Activity with Cyclic Selenenyl Sulfides: Participation of an NH???Se Hydrogen Bond through Stabilization of the Mixed Se?S Intermediate (Chem. Eur. J. 55/2019)
Modeling Thioredoxin Reductase-Like Activity with Cyclic Selenenyl Sulfides: Participation of an NH...Se Hydrogen Bond through Stabilization of the Mixed Se-S Intermediate
Cyclic telluride reagents with remarkable glutathione peroxidase-like activity for purification-free synthesis of highly pure organodisulfides
Coupling effects of thiol and urea-type groups for promotion of oxidative protein folding
Oxidative Protein Folding Using trans-3,4-Dihydroxyselenolane Oxide.
Characterization and optimization of two-chain folding pathways of insulin via native chain assembly
Protein Folding in the Presence of Water-Soluble Cyclic Diselenides with Novel Oxidoreductase and Isomerase Activities
Mechanism of radioprotection by dihydroxy-1-selenolane (DHS): Effect of fatty acid conjugation and role of glutathione peroxidase (GPx)
共同研究?競争的資金等の研究課題
Development and pharmacological investigation of novel diselenide compounds as a medicine for folding diseases
Development of an effective folding procedure for SS-containing proteins by using a micro flow chemistry
ResearchMapへ移動します
Contact Us
Inquiries about coverage
Public Affairs Division Public Affairs and Communications Department
Tel. 0463-63-4670(direct dialing)